Results
| PMID | 20455877 |
| Gene Name | RETN |
| Condition | Endometriosis |
| Association |
Associated |
| Population size | 84 |
| Population details | 84 (48 women with endometriosis, 36 women without endometriosis) |
| Sex | Female |
| Associated genes | Resistin |
| Other associated phenotypes |
Endometriosis |
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Am J Reprod Immunol. 2010 Nov;64(5):318-23. doi: Yi, Kyong Wook| Shin, Jung-Ho| Park, Hyun Tae| Kim, Tak| Kim, Sun Haeng| Hur, Jun-Young Department of Obstetrics and Gynecology, Korea University, Seoul, Korea. PROBLEM: The aim of this study was to investigate the concentration of resistin and adiponectin in the peritoneal fluid (PF) of patients with endometriosis. METHOD OF STUDY: PF sampling was obtained from women with (n = 48) and without endometriosis (n = 36), and the anthropometric indices of the patients were measured. Resistin and adiponectin concentrations in the PF were determined using the enzyme-linked immunosorbent assay. RESULTS: The mean concentration of PF resistin was significantly higher in women with endometriosis compared to the controls. PF resistin concentrations were not associated with any of the anthropometric indices. The PF adiponectin did not differ between the two groups, but showed a significant association with the weight, body mass index, and hip circumference. After adjusting for these factors, PF adiponectin expression was not associated with endometriosis. CONCLUSION: The findings of this study suggest a potent role for resistin in endometriosis. Further studies are needed to elucidate the biological implications of resistin in endometriosis. Mesh Terms: Adiponectin/analysis/immunology/metabolism| Ascitic Fluid/immunology/*metabolism| Body Mass Index| Body Weight| Endometriosis/immunology/*metabolism/pathology| Female| Humans| Regression Analysis| Resistin/immunology/*metabolism| Waist Circumfere |
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